Overview
The hero ingredient is salmon DNA PDRN, and you use it as a targeted treatment step. With an excellent 4.7 out of 5 from over 111 ratings, it is one of the best-reviewed pdrn & salmon dna in the range. It is one of the gentler options in the range, so it suits most skin types including sensitive skin.
Pros
- Well-rated at 4.7/5 across 111 reviews
- Built around salmon DNA PDRN, a genuinely on-trend active
- Gentle enough for daily use on most skin types
Cons
- Priced above the cheapest options in the range
- As a food-and-cosmetic product, results vary from person to person
At a glance
| Type | PDRN & Salmon DNA |
|---|
| Key ingredient | salmon DNA PDRN |
|---|
| Format | serum |
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| Routine step | Treatment (serum step) |
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| Best for skin type | Dry, Combination, Normal |
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| Sensitive-skin friendly | Yes, one of the gentler picks |
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| Rating | 4.7 / 5 from 111 ratings |
What buyers actually say
We read a sample of the Amazon reviews for this product and describe the pattern in our own words. It is a sample, not a survey of all 111 ratings, and we do not reproduce customer reviews.
Praise here centers on immediate plumpness and glow rather than long-term change, with reviewers describing skin that looks bouncier and better hydrated and rating the pair good value against Western equivalents. The texture notes are the most useful part: the peptide serum is thin with a faint scent, while the single-use ampoules are thicker, slower to sink in and leave a tacky finish that most say fades. Several entries in this sample are short and generically enthusiastic, which limits what can be drawn from them. No irritation was reported, and the small share of low ratings goes unexplained in what we read.
Praised for
- Skin looks plump, soft and glowing after use
- Strong value compared with Western equivalents
- Single-use ampoules keep the thicker serum fresh
- Results reported within a few weeks of daily use
Criticised for
- Ampoule serum is thick, slow to absorb and initially sticky
- Faint fragrance in the peptide serum
- Many reviews too generic to be informative
How the ratings break down
Amazon's own star distribution for this product, read on 2026-08-02. We show the one-star share too, because an average alone hides it.
5 star 81%
4 star 12%
3 star 5%
2 star 1%
1 star 1%
What is salmon DNA PDRN?
PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.
Ingredients as listed on Amazon
Copied from the Amazon listing on 2026-08-02. We have not verified this against the physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.
Show the ingredient list
Water, Glycerin, Dipropylene Glycol, Isopropyl Myristate, Glycereth-26, Niacinamide, 1,2- Hexanediol, Sodium DNA, Butylene Glycol, Polyglycerin-3, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Milt Extract, Tromethamine, Glyceryl Acrylate/Acrylic Acid Copolymer, PVM/MA Copolymer, Ethylhexylglycerin, Caprylyl Glycol, Fragrance, Melia Azadirachta Leaf Extract, Adenosine, Caprylyl/Capryl Glucoside, Sorbitan Oleate, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Disodium EDTA, Curcuma Longa (Turmeric) Root Extract, Cyanocobalamin, Hydrolyzed Collagen, Ubiquinone, Ocimum Sanctum Leaf Extract, Corallina Officinalis Extract, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Copper Tripeptide-1, Acetyl Hexapeptide-8, Salmon Egg Extract, Atelocollagen. Water (Aqua); Glycerin; Butylene Glycol; Polyglycerin-3; Methylpropanediol; Niacinamide; Glycereth-26; 1, 2-Hexanediol; Betaine; PEG-8; Methyl Gluceth-20; Methyl Gluceth-10; Carbomer; Tromethamine; Panthenol; Ethylhexylglycerin; C12-14 Alketh-12; Glyceryl Acrylate/Acrylic Acid Copolymer; Xanthan Gum; Adenosine; Disodium EDTA; Saccharide Hydrolysate; Cyanocobalamin; Salmon Egg Extract; Polyglyceryl-10 Laurate; Hydrogenated Lecithin; Soluble Elastin; Sodium DNA (1ppm); Microcrystalline Cellulose; Sodium Hyaluronate; Cellulose Gum; Hyaluronic Acid; Soluble Collagen; Sodium Hyaluronate Crosspolymer; Hydrolyzed Sodium Hyaluronate; Hydrolyzed Hyaluronic Acid; Glutathione; Sorbitan Laurate; Sodium Acetylated Hyaluronate; Hydroxypropyltrimonium Hyaluronate; Hydroxyethylcellulose; Acetyl Dipeptide-1 Cetyl Ester
Key features
- KOREAN GLASS GLOW SKIN
- SALMON DNA PDRN
- LONG LASTING HYDRATION
- Hydrating & Radiance-Boosting Salmon DNA Ampoule: Improves skin density with 58.7% hydration increase immed…
- One-Day Pink Drop Ampoule
Frequently asked questions
Is the medicube Intensive Moisture & Skin Plumping Set good for sensitive skin?
Yes, it is one of the gentler options in the range and suits most skin types, including sensitive skin. As always, patch test first.
How do you use the medicube Intensive Moisture & Skin Plumping Set?
Use it after toner, before moisturizer. Follow the directions on the pack, and always finish your morning routine with sunscreen.
Is the medicube Intensive Moisture & Skin Plumping Set worth it?
For the price, it is an easy recommendation: 4.7 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.
Check price on Amazon →