Overview
Medicube markets this on salmon DNA PDRN, and you use it as your daily moisturizer. With an excellent 4.6 out of 5 from over 7k ratings, it is one of the best-reviewed products in its range. Its Amazon listing does not flag strong actives, which is a filter on listing text rather than a safety assessment.
The summary above follows how Medicube markets this product. We also read the
published ingredient list line by line, and it tells a different story:
what the ingredient order actually says.
Pros
- Excellent 4.6/5 rating from 7k shoppers
- Marketed around salmon DNA PDRN, a genuinely on-trend active
- Listing flags no strong actives
- Lightweight texture that layers cleanly under other products
Cons
- Priced above the cheapest options in the range
At a glance
| Type | PDRN & Salmon DNA |
|---|
| Key ingredient | salmon DNA PDRN |
|---|
| Format | moisturizer |
|---|
| Size | 1.94 oz |
|---|
| Routine step | Moisturizer |
|---|
| Best for skin type | Dry, Sensitive, Combination, Normal |
|---|
| Sensitive-skin friendly | Its listing flags no strong actives |
|---|
| Rating | 4.6 / 5 from 28,569 ratings |
What buyers actually say
We read a sample of the Amazon reviews for this product and describe the pattern in our own words. It is a sample, not a survey of all 28,569 ratings, and we do not reproduce customer reviews.
Twelve reviews in our sample, ten at five stars, though a fair share are short and general, so the evidence is lighter than the count suggests. The recurring praise is that it feels lighter than the brand's collagen jelly cream while still moisturizing, absorbs without leaving grease, and does not pill under other steps. Sensitive-skin reviewers report no irritation. The measured comments come from reviewers who like it: slight residual tackiness, slow absorption on the first application before it improves, and no visible change yet to fine lines. Nine percent of all ratings sit at three stars or lower.
Praised for
- Lightweight but still moisturizing
- Absorbs without a greasy finish
- Less sticky than the brand's jelly cream
- No irritation reported by sensitive-skin users
Criticized for
- Slight tackiness still noticeable
- Slow absorption on first use
- No visible change to fine lines for some
- Many sample reviews too brief to weigh
How the ratings break down
Amazon's own star distribution for this product, read on 2026-09-30. We show the one-star share too, because an average alone hides it.
5 star 82%
4 star 9%
3 star 4%
2 star 2%
1 star 3%
5% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.
We cannot tell you what those reviewers said. Amazon.com now requires an
account to open the full review list, so the critical reviews are not readable from a public
page. We would rather say that than guess.
What is salmon DNA PDRN?
PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.
Ingredients, as listed by Medicube
Taken from Medicube's own product page on 2026-08-04. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.
Show the full ingredient list (59 ingredients)
Water, Glycerin, Niacinamide, Methylpropanediol, Propanediol, 1,2-Hexanediol, Dipropylene Glycol, Caprylic/Capric Triglyceride, Butylene Glycol, Glycereth-26, Arginine, Carbomer, Cetearyl Alcohol, Cetearyl Olivate, Ethylhexyl Palmitate, Sorbitan Olivate, Squalane, Ammonium Acryloyldimethyltaurate/VP Copolymer, Simethicone, Ethylhexylglycerin, Lithospermum Erythrorhizon Root Extract, Adenosine, Helianthus Annuus (Sunflower) Seed Oil, Polyacrylate-13, Sodium DNA, Disodium EDTA, Polyisobutene, Glyceryl Stearate, Hydrolyzed Sclerotium Gum, Pyrus Communis (Pear) Fruit Extract, Alkanna Tinctoria Root Extract, Rosa Damascena Flower Water, Iris Florentina Root Extract, Polysorbate 20, Cucumis Melo (Melon) Fruit Extract, Sorbitan Isostearate, Hedera Helix (Ivy) Leaf/Stem Extract, Glutathione, Sodium Hyaluronate, Octyldodecanol, Salmon Egg Extract, Hydroxypropyltrimonium Hyaluronate, Tocopherol, Hydrogenated Lecithin, Ceramide NP, Cyanocobalamin, Thioctic Acid, Sodium Acetylated Hyaluronate, Hydrolyzed Collagen Extract, Hydrolyzed Hyaluronic Acid, Acetyl Hexapeptide-8, Copper Tripeptide-1, Caprylyl Glycol, Hyaluronic Acid, Palmitoyl Pentapeptide-4, Palmitoyl Hexapeptide-12, Sodium Hyaluronate Crosspolymer, Hydrolyzed Sodium Hyaluronate, Potassium Hyaluronate
What the listing says
Medicube's own description of this product, as
published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not
verified the claims in it.
- Premium Salmon DNA PDRN Capsule
- Lightweight non-sticky texture
- Customizable Mark-Blast Mix
- Achieve Korean glass glow skin
- Daily moisturizing cream for sensitive skin
Full listing title: Capsule Cream with Salmon DNA PDRN Pink Collagen | Lightweight Moisturizing Cream with PDRN, Niacinamide for Uneven Skin Tone and Texture, Glow hydration | Korean Skincare, 1.94 oz
Frequently asked questions
Is the medicube Capsule Cream with Salmon DNA PDRN good for sensitive skin?
We cannot tell you that. What we can say is that its Amazon listing does not flag strong actives, which is a filter on listing text, not a safety assessment. If your skin is reactive or you have a diagnosed condition, patch test first and ask a pharmacist, GP or dermatologist.
How do you use the medicube Capsule Cream with Salmon DNA PDRN?
Use it as the last step of your routine (before sunscreen in the morning). Follow the directions on the pack, and always finish your morning routine with sunscreen.
Is the medicube Capsule Cream with Salmon DNA PDRN worth it?
For the price, it is an easy recommendation: 4.6 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.
Check price on Amazon →