Medicube Cleansing Oil PDRN Mild for Pore & Sebum Care

Overview

The hero ingredient is salmon DNA PDRN, and you use it as your daily cleanse. With a strong 4.4 out of 5 from 112 ratings, it is a well-liked pick. It uses active ingredients, so patch test first and introduce it slowly if your skin is reactive.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

At a glance

How the ratings break down

Amazon's own star distribution for this product, read on 2026-10-28. We show the one-star share too, because an average alone hides it.

11% of these ratings are one or two stars. That is well above the 6% median for the Medicube range. This is one of the more divisive products in the catalogue: most people like it, but a meaningful minority does not, and the average hides that.

We cannot tell you what those reviewers said. Amazon.com now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is salmon DNA PDRN?

PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.

What we can and cannot tell you about this cleansing oil

• We have not found this oil, with its ingredient list, in Medicube's own US store; the cleansing oil listed there is the Zero Pore Blackhead Deep Cleansing Oil, a different product. So everything here is read from the Amazon listing, and none of it is checked against an ingredient order.
• The listing's ingredient story is PDRN, niacinamide, hyaluronic acid and LHA. In a cleansing oil all four are on the skin for a minute or two before they are emulsified and rinsed away, which limits what any of them can do. The cleansing itself is the job to judge.
• On that job the listing makes concrete, checkable promises: it removes waterproof makeup and sunscreen, turns milky with water and rinses clean. Those are the things to test in the first week, and a cleansing oil that does them well is worth keeping whatever its actives.
• The listing calls it non-comedogenic and eye-irritation tested. Both are the brand's own test claims, and we cannot see the data behind them.

Our read

Judge this as a cleansing oil, not as a PDRN product: what matters is whether it removes sunscreen and makeup and rinses off without residue. Without a published list we cannot tell you what the oil phase is made of or whether fragrance is present, so sensitive and acne-prone users should patch-test before committing.

Who should skip this

• You want PDRN to do something for your skin. In a rinse-off oil it is gone within minutes.
• You need to check every ingredient before buying. We could not find a published list for this oil.
• Your skin breaks out from cleansing oils that do not rinse fully. Test it on a small area first.

What the listing says

Medicube's own description of this product, as published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not verified the claims in it.

• [POWERFUL YET GENTLE CLEANSING] Removes waterproof makeup, sunscreen, and excess sebum while helping exfoliate with LHA and keep skin hydrated with Hyaluronic Acid.
• [PDRN CARE FOR UNEVEN SKIN TONE] Formulated with Liposomal Salmon PDRN and Niacinamide to help improve the look of dull, uneven skin tone while cleansing.
• [LIGHTWEIGHT WATERY OIL TEXTURE] A lightweight, watery oil that quickly turns milky with water and rinses away cleanly, leaving skin feeling fresh without a greasy finish.
• [MILD ENOUGH FOR EVERYDAY] Dermatologist-tested, non-comedogenic, and eye irritation tested for gentle daily use. Suitable for all skin types, including oily and combination skin.
• [HOW TO USE] Pump 2 - 3 times onto dry hands and massage over dry skin. Add water until the oil turns milky, then rinse thoroughly with water.

Full listing title: medicube Cleansing Oil PDRN Mild for Pore & Sebum Care, with Low irritation

Frequently asked questions

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