Overview
Medicube markets this on salmon DNA PDRN, and you use it as a targeted treatment step. With an excellent 4.6 out of 5 from over 2k ratings, it is one of the best-reviewed products in its range. Its Amazon listing does not flag strong actives, which is a filter on listing text rather than a safety assessment.
The summary above follows how Medicube markets this product. We also read the
published ingredient list line by line, and it tells a different story:
what the ingredient order actually says.
Pros
- Excellent 4.6/5 rating from 2k shoppers
- Marketed around salmon DNA PDRN, a genuinely on-trend active
- Affordable for what it is, undercutting many Western equivalents
- Listing flags no strong actives
Cons
- Sold mainly through Amazon, so stock and price can move
At a glance
| Type | PDRN & Salmon DNA |
|---|
| Key ingredient | salmon DNA PDRN |
|---|
| Format | serum |
|---|
| Size | 2.02 fl.oz |
|---|
| Routine step | Treatment (serum step) |
|---|
| Best for skin type | Dry, Combination, Normal |
|---|
| Sensitive-skin friendly | Its listing flags no strong actives |
|---|
| Rating | 4.6 / 5 from 2,868 ratings |
What buyers actually say
We read a sample of the Amazon reviews for this product and describe the pattern in our own words. It is a sample, not a survey of all 2,868 ratings, and we do not reproduce customer reviews.
Reviewers in our sample treat this less as a treatment step and more as an all-day refresher, using it before makeup, over makeup and again mid-afternoon. The recurring praise is immediate hydration with a plump, dewy look, plus the fact that it does not disturb makeup already on the face. Dissent is limited. One four-star reviewer found it tackier than advertised and prefers pressing it in by hand so the spray misses her lashes. The single one-star in the sample concerns a bottle that arrived broken and leaking, which is a shipping problem rather than a formula one.
Praised for
- Instant hydration and a plump, dewy look
- Refreshes makeup without disturbing it
- Light enough for repeated use through the day
- Layers well with the rest of a routine
Criticized for
- Slightly sticky and noticeable on the skin for some
- Spray mist lands on lashes and eyelids
- One bottle arrived broken and leaking
How the ratings break down
Amazon's own star distribution for this product, read on 2026-10-01. We show the one-star share too, because an average alone hides it.
5 star 81%
4 star 10%
3 star 5%
2 star 1%
1 star 3%
4% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.
We cannot tell you what those reviewers said. Amazon.com now requires an
account to open the full review list, so the critical reviews are not readable from a public
page. We would rather say that than guess.
What is salmon DNA PDRN?
PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.
Ingredients, as listed by Medicube
Taken from Medicube's own product page on 2026-08-06. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.
Show the full ingredient list (47 ingredients)
COLLAGEN WATER(80.9%), ISOPROPYL MYRISTATE, GLYCERIN, NIACINAMIDE, 1,2-HEXANEDIOL, WATER, SODIUM CHLORIDE, LIMNANTHES ALBA (MEADOWFOAM) SEED OIL, BUTYLENE GLYCOL, HYDROXYACETOPHENONE, PROPANEDIOL, GELLAN GUM, SODIUM DNA(1,081ppm), HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, ETHYLHEXYLGLYCERIN, ADENOSINE, TRIETHYL CITRATE, ZEA MAYS (CORN) KERNEL EXTRACT, ALKANNA TINCTORIA ROOT EXTRACT, DISODIUM EDTA, TOCOPHEROL, HYALURONIC ACID, HYDROLYZED HYALURONIC ACID, SODIUM HYALURONATE, COLLAGEN(10.8ppm), FRUCTAN, BETULA ALBA BARK/LEAF EXTRACT, RICINUS COMMUNIS (CASTOR) SEED OIL, GLUCOSE, CYMBOPOGON CITRATUS LEAF OIL, ILLICIUM VERUM (ANISE) FRUIT/SEED OIL, SQUALANE, GLUTATHIONE, HYDROLYZED ELASTIN, SALMON EGG EXTRACT, MALTODEXTRIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, HYDROGENATED LECITHIN, CERAMIDE NP, SODIUM CITRATE, CAPRYLYL GLYCOL, SODIUM PHOSPHATE, CITRIC ACID, PEARL EXTRACT, CYANOCOBALAMIN, SH-OLIGOPEPTIDE-1
What the listing says
Medicube's own description of this product, as
published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not
verified the claims in it.
- [Dual-Texture Innovation for Every Glow] A unique jelly-mist formula that combines the power of a serum wit…
- [Quick Hydration, Lasting Radiance] Enriched with 99% purity Salmon PDRN and Collagen, this dual-texture fo…
- [Innovative Jelly Textured Serum & Mist] Formulated with an optimal 1:9 oil-to-jelly ratio to keep ingredie…
- [Glow-Enhancing Complex] Niacinamide, Glutathione, Ceramide, and Hyaluronic Acid work together to boost cla…
- [On-The-Go Glow] Lightweight, travel-friendly mist designed for morning prep, mid-day refresh, or post-work…
- [How to Use] For serum-like care, shake and spray close for a richer texture that absorbs deeply.
Full listing title: Jelly Mist Serum with Pink PDRN Collagen, 2.02 fl.oz | Dual-Texture Glow Spray with Niacinamide, Glutathione, Hyaluronic Acid, Ceramide - Hydration, Radiance, Plump-Looking Skin
Frequently asked questions
Is the medicube Jelly Mist Serum with Pink PDRN good for sensitive skin?
We cannot tell you that. What we can say is that its Amazon listing does not flag strong actives, which is a filter on listing text, not a safety assessment. If your skin is reactive or you have a diagnosed condition, patch test first and ask a pharmacist, GP or dermatologist.
How do you use the medicube Jelly Mist Serum with Pink PDRN?
Use it after toner, before moisturizer. Follow the directions on the pack, and always finish your morning routine with sunscreen.
Is the medicube Jelly Mist Serum with Pink PDRN worth it?
For the price, it is an easy recommendation: 4.6 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.
Check price on Amazon →