Independent, in-depth reviews of the Medicube range. As an Amazon Associate we earn from qualifying purchases.
medicube Exosome Shot Azelaic Acid 7,500 PPM Spicule Facial Serum
medicube

Medicube Exosome Shot Azelaic Acid 7

We have not used this product. This is a research write-up built from the Amazon.com listing, its ingredient list and what buyers report, not a hands-on test. What that means.

★4.5 / 5 ★★★★★ 349 ratings
1K+ bought #6 in Facial Serums Amazon, 2026-10-30
Quick verdict

A well-liked, 4.5-star concentrated serum, marketed around niacinamide. Best for glow.

$13.90$23.99-42%

Amazon price on 2026-10-30 · In Stock. Prices change often, check Amazon for today's price.

Check price on Amazon →

As an Amazon Associate we earn from qualifying purchases.

Overview

The hero ingredient is niacinamide, and you use it as a targeted treatment step. With a strong 4.5 out of 5 from 307 ratings, it is a well-liked pick. It uses active ingredients, so patch test first and introduce it slowly if your skin is reactive.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

Pros

  • Well-rated at 4.5/5 across 307 reviews
  • Built around niacinamide, a genuinely on-trend active

Cons

  • Contains actives that can irritate reactive skin, so patch test first
  • Priced above the cheapest options in the range
  • As a food-and-cosmetic product, results vary from person to person

At a glance

TypePDRN & Salmon DNA
Key ingredientniacinamide
Formatconcentrated serum
Routine stepTreatment (serum step)
Best for skin typeDry, Combination, Normal
Sensitive-skin friendlyUse with care, contains actives
Rating4.5 / 5 from 349 ratings

How the ratings break down

Amazon's own star distribution for this product, read on 2026-10-28. We show the one-star share too, because an average alone hides it.

5 star 76%
4 star 12%
3 star 5%
2 star 3%
1 star 4%

7% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.

We cannot tell you what those reviewers said. Amazon.com now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is niacinamide?

Niacinamide (vitamin B3) helps with uneven tone, visible pores and oil control, and is well tolerated by most skin types.

Ingredients, as listed by Medicube

Taken from Medicube's own product page on 2026-10-18. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.

Show the full ingredient list (47 ingredients)

Water, Butylene Glycol, Dipropylene Glycol, Niacinamide, Glycerin, Sodium Polyacrylate, 1,2-Hexanediol, Caprylyl Glycol, Cetearyl Olivate, Phenyl Trimethicone, Sorbitan Olivate, Hydrolyzed Sponge, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Glyceryl Acrylate/Acrylic Acid Copolymer, Ethylhexylglycerin, Calcium Aluminum Borosilicate, Coccinia Indica Fruit Extract, Adenosine, Disodium EDTA, PVM/MA Copolymer, Ocimum Sanctum Leaf Extract, Solanum Melongena (Eggplant) Fruit Extract, Aloe Barbadensis Flower Extract, Dipotassium Glycyrrhizate, Azelaic Acid(100 ppm), Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Lactobacillus Extracellular Vesicles(50 ppm), Isopentyldiol, Betaine Salicylate, Citric Acid, Pantothenic Acid, Milk Exosomes(10 ppm), Propanediol, Polyglycerin-3, Hydrolyzed Collagen, Sodium Hyaluronate, Collagen, Centella Asiatica Extract, Asiaticoside, Madecassic Acid, Ceramide NP, Asiatic Acid, Sorbitan Stearate, Palmitic Acid, Salicylic Acid

What the ingredient order actually tells you

  • The azelaic acid is declared on the manufacturer's list, and the number is small: Azelaic Acid (100 ppm) at 26th of 47. That is 0.01%. The listing's '99% purity' describes the raw material, not the amount in the bottle.
  • Niacinamide at fourth is the substantial active, consistent with the 5% the listing states. Hydrolyzed sponge, the spicules, sits 12th, so expect some prickle even though azelaic acid leads the name.
  • The exosomes are declared too: lactobacillus extracellular vesicles 29th at 50 ppm and milk exosomes 34th at 10 ppm. The 7,500 PPM in the product name matches none of these declared strengths, and the list does not say what it measures.
  • The plant cluster that recurs across this range, neem, coccinia, holy basil, eggplant, aloe, turmeric and coralline, sits between 13th and 28th. Salicylic acid is the very last entry, at 47th.
Our read

A niacinamide and spicule serum with azelaic acid at a declared 0.01%, far below the 10% or more that leave-on azelaic products usually carry. If you came for azelaic acid's effect on redness and marks, the list says this is not the product for it. As a niacinamide booster with a mild spicule texture effect, it is coherent.

Who should skip this

  • You want azelaic acid in a working amount. The list declares 100 ppm, which is 0.01%.
  • Your skin dislikes spicules. Hydrolyzed sponge sits 12th.
  • You already use a 5% niacinamide product. This repeats it as the fourth ingredient.

A note on how we read that list. Ingredient lists run in descending order of concentration, but only for ingredients above 1%. Below that, the order is up to the manufacturer, so a low position tells you something is present at a low level, not exactly how much. We do not guess at percentages. FDA labeling guide.

What the listing says

Medicube's own description of this product, as published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not verified the claims in it.

Full listing title: medicube Exosome Shot Azelaic Acid 7,500 PPM Spicule Facial Serum

Frequently asked questions

Is the medicube Exosome Shot Azelaic Acid 7,500 PPM good for sensitive skin?

It contains active ingredients, so it can be too much for very reactive skin. Patch test first, introduce it slowly, and skip it if your barrier is compromised.

How do you use the medicube Exosome Shot Azelaic Acid 7,500 PPM?

Use it after toner, before moisturizer. Follow the directions on the pack, and always finish your morning routine with sunscreen.

Is the medicube Exosome Shot Azelaic Acid 7,500 PPM worth it?

For the price, it is an easy recommendation: 4.5 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.

Check price on Amazon →

Shopping for a specific problem? Medicube for Glow and Hydration · Medicube for Dry Skin

More in PDRN & Salmon DNA

See all →