Overview
The hero ingredient is niacinamide, and you use it as a targeted treatment step. With a strong 4.5 out of 5 from 307 ratings, it is a well-liked pick. It uses active ingredients, so patch test first and introduce it slowly if your skin is reactive.
The summary above follows how Medicube markets this product. We also read the
published ingredient list line by line, and it tells a different story:
what the ingredient order actually says.
Pros
- Well-rated at 4.5/5 across 307 reviews
- Built around niacinamide, a genuinely on-trend active
Cons
- Contains actives that can irritate reactive skin, so patch test first
- Priced above the cheapest options in the range
- As a food-and-cosmetic product, results vary from person to person
At a glance
| Type | PDRN & Salmon DNA |
|---|
| Key ingredient | niacinamide |
|---|
| Format | concentrated serum |
|---|
| Routine step | Treatment (serum step) |
|---|
| Best for skin type | Dry, Combination, Normal |
|---|
| Sensitive-skin friendly | Use with care, contains actives |
|---|
| Rating | 4.5 / 5 from 349 ratings |
How the ratings break down
Amazon's own star distribution for this product, read on 2026-10-28. We show the one-star share too, because an average alone hides it.
5 star 76%
4 star 12%
3 star 5%
2 star 3%
1 star 4%
7% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.
We cannot tell you what those reviewers said. Amazon.com now requires an
account to open the full review list, so the critical reviews are not readable from a public
page. We would rather say that than guess.
What is niacinamide?
Niacinamide (vitamin B3) helps with uneven tone, visible pores and oil control, and is well tolerated by most skin types.
Ingredients, as listed by Medicube
Taken from Medicube's own product page on 2026-10-18. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.
Show the full ingredient list (47 ingredients)
Water, Butylene Glycol, Dipropylene Glycol, Niacinamide, Glycerin, Sodium Polyacrylate, 1,2-Hexanediol, Caprylyl Glycol, Cetearyl Olivate, Phenyl Trimethicone, Sorbitan Olivate, Hydrolyzed Sponge, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Glyceryl Acrylate/Acrylic Acid Copolymer, Ethylhexylglycerin, Calcium Aluminum Borosilicate, Coccinia Indica Fruit Extract, Adenosine, Disodium EDTA, PVM/MA Copolymer, Ocimum Sanctum Leaf Extract, Solanum Melongena (Eggplant) Fruit Extract, Aloe Barbadensis Flower Extract, Dipotassium Glycyrrhizate, Azelaic Acid(100 ppm), Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Lactobacillus Extracellular Vesicles(50 ppm), Isopentyldiol, Betaine Salicylate, Citric Acid, Pantothenic Acid, Milk Exosomes(10 ppm), Propanediol, Polyglycerin-3, Hydrolyzed Collagen, Sodium Hyaluronate, Collagen, Centella Asiatica Extract, Asiaticoside, Madecassic Acid, Ceramide NP, Asiatic Acid, Sorbitan Stearate, Palmitic Acid, Salicylic Acid
What the listing says
Medicube's own description of this product, as
published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not
verified the claims in it.
- One Exosome Shot for Daily Hydration & Recovery Care: Delivers concentrated care in a single pump - formulated with 15 million exosomes, 99% purity azelaic acid, and 5% niacinamide to deeply hydrate and support smoother post-spot texture care. *One Exosome Shot refers to one pump of product
- Pre-Care for Trouble-Prone, Reactive Skin: Start your routine before visible concerns appear. This fast-absorbing ampoule helps calm unbalanced skin - while promoting a clearer-looking skin with 99% Purity azelaic acid
- Post-Care improve for Uneven Tone & Texture: Powered by 30μm exosomes - *25x smaller than pores - for deep absorption. Targets uneven tone and rough skin texture *Clinical Trial Tested by the 'P&K Skin research center'
Full listing title: medicube Exosome Shot Azelaic Acid 7,500 PPM Spicule Facial Serum
Frequently asked questions
Is the medicube Exosome Shot Azelaic Acid 7,500 PPM good for sensitive skin?
It contains active ingredients, so it can be too much for very reactive skin. Patch test first, introduce it slowly, and skip it if your barrier is compromised.
How do you use the medicube Exosome Shot Azelaic Acid 7,500 PPM?
Use it after toner, before moisturizer. Follow the directions on the pack, and always finish your morning routine with sunscreen.
Is the medicube Exosome Shot Azelaic Acid 7,500 PPM worth it?
For the price, it is an easy recommendation: 4.5 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.
Check price on Amazon →