Medicube PDRN Pink Peptide Ampoule Sheet Mask 6EA

Overview

The hero ingredient is salmon DNA PDRN, and you use it as a targeted treatment step. With an excellent 4.7 out of 5 from over 295 ratings, it is one of the best-reviewed pdrn & salmon dna in the range. It is one of the gentler options in the range, so it suits most skin types including sensitive skin.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

At a glance

How the ratings break down

Amazon's own star distribution for this product, read on 2026-10-28. We show the one-star share too, because an average alone hides it.

1% of these ratings are one or two stars. That is below the 6% median for the Medicube range, so opinion on this one is unusually consistent.

We cannot tell you what those reviewers said. Amazon.com now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is salmon DNA PDRN?

PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.

Ingredients, as listed by Medicube

Taken from Medicube's own product page on 2026-10-18. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.

Show the full ingredient list (55 ingredients)

Water, Glycerin, Dipropylene Glycol, Niacinamide,1,2-Hexanediol, Glycereth-26, Erythritol, Glyceryl Glucoside, Arginine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Methyl Gluceth-20, Ethylhexylglycerin, Polyglyceryl-10 Laurate, Xanthan Gum, Adenosine, Butyrospermum Parkii (Shea) Butter, Caprylic/Capric Triglyceride, Olea Europaea (Olive) Fruit Oil, Hydrogenated Lecithin, Squalane, Butylene Glycol, Disodium EDTA, Hydroxyethylcellulose, Polyglutamic Acid, Melia Azadirachta Flower Extract, Ocimum Sanctum Leaf Extract, Cyanocobalamin, Melia Azadirachta Leaf Extract, Glyceryl Acrylate/Acrylic Acid Copolymer, Sodium DNA, Biosaccharide Gum-1, Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Ceramide NP, Cholesterol, Rosa Damascena Flower Oil, Phytosphingosine, Propanediol, Sodium Hyaluronate, Lecithin, Collagen Extract, Hydroxypropyltrimonium Hyaluronate, Glycolipids, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Acetyl Hexapeptide-8, Glutathione, Hyaluronic Acid, Oligopeptide-29, Oligopeptide-32, Hydrolyzed Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Potassium Hyaluronate, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1

What the ingredient order actually tells you

• The six-sheet box and the ten-sheet box share one manufacturer list, 55 entries long. Our reading of the ten-sheet box applies here unchanged: niacinamide sits fourth and the sodium DNA 30th. This page looks at the rest of the essence.
• This is a richer essence than most sheet masks carry. Shea butter sits 16th, olive fruit oil 18th and squalane 20th, held together by polyglyceryl-10 laurate at 13th, so expect a more cushioned finish than the watery kind.
• Between 25th and 33rd sits a cluster of plant extracts, neem, holy basil, turmeric and coralline seaweed, that recurs across this range: neem and coralline also appear in the TXA capsule cream, and all four in the azelaic acid Exosome Shot. It reads as a house blend, and at these positions it is a supporting note.
• Rose flower oil at 36th is the one scent-bearing oil on the list, and glutathione, a name the box does not lead with, sits 47th.

Our read

Same formula, smaller box: a well-cushioned niacinamide sheet mask with the PDRN its name leads with sitting 30th. The six-sheet pack suits a trial or an occasional habit; if you already know you like the essence, the ten-sheet box gives you the same list in larger quantity.

Who should skip this

• Oily skin dislikes a rich finish. Shea butter at 16th and olive oil at 18th make this a heavier essence than most masks.
• You want the PDRN to be the point. In both box sizes it sits 30th of 55.
• Rose oil has irritated your skin before. It is low on the list at 36th, but a sheet mask holds it against your face for the whole session.

A note on how we read that list. Ingredient lists run in descending order of concentration, but only for ingredients above 1%. Below that, the order is up to the manufacturer, so a low position tells you something is present at a low level, not exactly how much. We do not guess at percentages. FDA labeling guide.

What the listing says

Medicube's own description of this product, as published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not verified the claims in it.

• [Encapsulated Sodium DNA Complex for Long-Lasting Hydration] Powered by Encapsulated Sodium DNA Complex, designed to help maintain long-lasting, comfortable hydration. A specially engineered sheet process helps lock in moisture, delivering a comfortably hydrated feel without heaviness.
• [Signature Salmon PDRN Ampoule, Now in a Mask] Inspired by medicube’s signature Salmon DNA PDRN ampoule, this mask delivers ampoule-like care in a sheet format. Infused with PDRN, Niacinamide, and Peptides to support clearer-looking, balanced, and radiant skin.
• [Second-Skin Fit Prep Mask] Features an ultra-thin skin fit sheet designed to adhere smoothly across the face for even, gap-free care. Lightweight and comfortable, making it ideal as a makeup-prep mask to help leave skin feeling hydrated, smooth, and naturally glowy before makeup.

Full listing title: medicube PDRN Pink Peptide Ampoule Sheet Mask 6EA

Frequently asked questions

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