Independent, in-depth reviews of the Medicube range. As an Amazon Associate we earn from qualifying purchases.
medicube Zero Pore One Day 10 Peptide Serum
medicube

Medicube Zero Pore One Day 10 Peptide Serum

We have not used this product. This is a research write-up built from the Amazon.com listing, its ingredient list and what buyers report, not a hands-on test. What that means.

★4.6 / 5 ★★★★★ 392 ratings
6K+ bought #174 in Facial Serums Amazon, 2026-10-29
Quick verdict

An excellent, 4.6-star serum, marketed around niacinamide. Best for congestion.

$19.80$21.80-9%

Amazon price on 2026-10-29 · In Stock. Prices change often, check Amazon for today's price.

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Overview

The hero ingredient is niacinamide, and you use it as a targeted treatment step. With an excellent 4.6 out of 5 from over 352 ratings, it is one of the best-reviewed zero pore & pore care in the range. It uses active ingredients, so patch test first and introduce it slowly if your skin is reactive.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

Pros

  • Well-rated at 4.6/5 across 352 reviews
  • Built around niacinamide, a genuinely on-trend active

Cons

  • Contains actives that can irritate reactive skin, so patch test first
  • Priced above the cheapest options in the range
  • As a food-and-cosmetic product, results vary from person to person

At a glance

TypeZero Pore & Pore Care
Key ingredientniacinamide
Formatserum
Routine stepTreatment (serum step)
Best for skin typeOily, Sensitive, Combination, Normal
Sensitive-skin friendlyUse with care, contains actives
Rating4.6 / 5 from 392 ratings

How the ratings break down

Amazon's own star distribution for this product, read on 2026-10-28. We show the one-star share too, because an average alone hides it.

5 star 80%
4 star 10%
3 star 5%
2 star 3%
1 star 2%

5% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.

We cannot tell you what those reviewers said. Amazon.com now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is niacinamide?

Niacinamide (vitamin B3) helps with uneven tone, visible pores and oil control, and is well tolerated by most skin types.

Ingredients, as listed by Medicube

Taken from Medicube's own product page on 2026-08-05. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.

Show the full ingredient list (60 ingredients)

Water (Aqua), Methylpropanediol, Glycerin, Propanediol, Niacinamide, Tromethamine, 1,2-Hexanediol, Polyglycerin-3, Lactic Acid, Dimethicone, Gluconolactone, Salicylic Acid, Hydroxyethylcellulose, Sodium Polyacryloyldimethyl Taurate, Lecithin, C12-14 Alketh-12, Allantoin, Citric Acid, Ethylhexylglycerin, Adenosine, Butylene Glycol, Dextrin, Glycolic Acid, Sodium Citrate, Gardenia Florida Fruit Extract, Trisodium Phosphate, Capryloyl Salicylic Acid, Myosotis Sylvatica Flower/Leaf/Stem Extract, Hemerocallis Fulva Flower Extract, Stellaria Media (Chickweed) Extract, Lactobacillus Ferment Lysate, Taraxacum Officinale (Dandelion) Leaf Extract, Lactobacillus Ferment, Caprylic/Capric Triglyceride, Sorbitan Laurate, Cetyl Palmitate, Sorbitan Stearate, Polysorbate 80, Caprylyl Glycol, Acetyl Glutamine, Acetyl Dipeptide-1 Cetyl Ester, Bacillus/Soybean Ferment Extract, Sodium Benzoate, Ulmus Davidiana Root Extract, Pueraria Lobata Root Extract, Pinus Palustris Leaf Extract, Oenothera Biennis (Evening Primrose) Flower Extract, Hydrogenated Lecithin, Palmitoyl Tripeptide-5, Acetyl Hexapeptide-1, Tocopherol, Acetyl Octapeptide-3, Sodium Hyaluronate, Palmitoyl Tetrapeptide-10, Folic Acid, Copper Tripeptide-1, Oligopeptide-3, Oligopeptide-2, Oligopeptide-1, Hexapeptide-11

What the ingredient order actually tells you

  • The name counts ten peptides and the list delivers ten, which is how we know this list is the right one. They are also all at the back: from acetyl dipeptide-1 at 41st to hexapeptide-11 closing the list at 60th. Copper tripeptide sits 56th.
  • The acids are the real product. Lactic acid sits 9th, gluconolactone 11th and salicylic acid 12th, with glycolic acid 23rd and a second salicylate at 27th. Four acid families, three of them inside the top twelve.
  • Niacinamide sits 5th, adenosine 20th and dimethicone 10th for slip. That upper section is a pore and oil product, not a firming one.
  • So the name sells peptides and the order sells exfoliation. Neither is dishonest, but they point at different shoppers, and the one the order serves is the oily, congested, texture-focused one.
Our read

A well-built exfoliating serum wearing a peptide name. Three acid families sit inside the top twelve and the ten peptides sit in the last twenty, so read this as a pore and texture treatment with a firming garnish. On oily or congested skin that is a good thing to be. If you came for the peptides, you are paying for a tail.

Who should skip this

  • You came for the peptides. All ten sit in the last twenty entries of 60.
  • Your skin is dry, sensitized or on a retinoid. Four acid families in one serum is a lot to layer.
  • You want one gentle daily step. This is a treatment, not a base layer.

A note on how we read that list. Ingredient lists run in descending order of concentration, but only for ingredients above 1%. Below that, the order is up to the manufacturer, so a low position tells you something is present at a low level, not exactly how much. We do not guess at percentages. FDA labeling guide.

What the listing says

Medicube's own description of this product, as published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not verified the claims in it.

Full listing title: medicube Zero Pore One Day 10 Peptide Serum

Frequently asked questions

Is the medicube Zero Pore One Day 10 Peptide good for sensitive skin?

It contains active ingredients, so it can be too much for very reactive skin. Patch test first, introduce it slowly, and skip it if your barrier is compromised.

How do you use the medicube Zero Pore One Day 10 Peptide?

Use it after toner, before moisturizer. Follow the directions on the pack, and always finish your morning routine with sunscreen.

Is the medicube Zero Pore One Day 10 Peptide worth it?

For the price, it is an easy recommendation: 4.6 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.

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Shopping for a specific problem? Medicube for Pores and Blackheads · Medicube for Oily Skin

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