Overview
Medicube markets this on salmon DNA PDRN, and you use it as a targeted treatment step. With a strong 4.5 out of 5 from 592 ratings, it is a well-liked pick. Its Amazon listing does not flag strong actives, which is a filter on listing text rather than a safety assessment.
The summary above follows how Medicube markets this product. We also read the
published ingredient list line by line, and it tells a different story:
what the ingredient order actually says.
Pros
- Well-rated at 4.5/5 across 592 reviews
- Marketed around salmon DNA PDRN, a genuinely on-trend active
- Listing flags no strong actives
Cons
- Priced above the cheapest options in the range
At a glance
| Type | PDRN & Salmon DNA |
|---|
| Key ingredient | salmon DNA PDRN |
|---|
| Format | serum |
|---|
| Size | 3.71 fl. Oz |
|---|
| Routine step | Treatment (serum step) |
|---|
| Best for skin type | Dry, Sensitive, Combination, Normal |
|---|
| Sensitive-skin friendly | Its listing flags no strong actives |
|---|
| Rating | 4.5 / 5 from 908 ratings |
What buyers actually say
We read a sample of the Amazon reviews for this product and describe the pattern in our own words. It is a sample, not a survey of all 908 ratings, and we do not reproduce customer reviews.
The defining trait in this sample is how thin the formula is. Reviewers repeatedly compare the consistency to water or toner, note that two drops cover face and neck, and say the bottle is generous. Oily and acne-prone buyers, including one dealing with Florida humidity, treat that weightlessness as the main selling point, and several report skin looking plumper and makeup sitting well over it. Some also use it on dry patches elsewhere on the body. The counterweight is straightforward: a three-star reviewer with dry, mature skin found it too insubstantial and distinct from the brand's thicker concentrated PDRN serum, and one oily-skinned user noticed shine hours later after applying too much.
Praised for
- Extremely light, watery texture that absorbs instantly
- Large bottle and very little product needed per use
- Suits oily, acne-prone skin and hot weather
- Layers well and sits comfortably under makeup
Criticized for
- Too lightweight to moisturize dry or mature skin adequately
- Noticeably different from the brand's thicker concentrated PDRN serum
- One reviewer saw oiliness later in the day when applying too much
How the ratings break down
Amazon's own star distribution for this product, read on 2026-10-01. We show the one-star share too, because an average alone hides it.
5 star 79%
4 star 9%
3 star 7%
2 star 2%
1 star 3%
5% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.
We cannot tell you what those reviewers said. Amazon.com now requires an
account to open the full review list, so the critical reviews are not readable from a public
page. We would rather say that than guess.
What is salmon DNA PDRN?
PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.
Ingredients, as listed by Medicube
Taken from Medicube's own product page on 2026-08-05. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.
Show the full ingredient list (39 ingredients)
WATER (AQUA), PROPANEDIOL, BUTYLENE GLYCOL, GLYCERIN, NIACINAMIDE, 1,2-HEXANEDIOL, SODIUM DNA, XANTHAN GUM, ETHYLHEXYLGLYCERIN, ADENOSINE, CITRIC ACID, SODIUM PHYTATE, CYANOCOBALAMIN, LEONTOPODIUM ALPINUM CALLUS CULTURE EXTRACT, FISH EXTRACT, LECITHIN, DIPOTASSIUM GLYCYRRHIZATE, SALMON EGG EXTRACT, ARGININE, CHOLESTEROL, CERAMIDE NP, COPPER TRIPEPTIDE-1, PEARL EXTRACT, SODIUM HYALURONATE, DIPEPTIDE-2, HYDROXYPROPYLTRIMONIUM HYALURONATE, OLIGOPEPTIDE-1, PALMITOYL PENTAPEPTIDE-4, TRIPEPTIDE-1, HYDROLYZED COLLAGEN, HYDROLYZED HYALURONIC ACID, SODIUM ACETYLATED HYALURONATE, HYALURONIC ACID, HYDROLYZED SODIUM HYALURONATE, SODIUM HYALURONATE CROSSPOLYMER, POTASSIUM HYALURONATE, HYDROLYZED CONCHIOLIN PROTEIN, PEARL POWDER, SUCCINOYL ATELOCOLLAGEN
What the listing says
Medicube's own description of this product, as
published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not
verified the claims in it.
- ULTRA-LIGHT, NON-STICKY FORMULA
- FAST ABSORPTION WITH NANO DELIVERY
- HYDRATION & FRESH GLOW CARE
- RADIANCE & EVEN-LOOKING SKIN CARE
- GENTLE DAILY SOOTHING & CALMING
- FREE FROM ARTIFICIAL FRAGRANCE & COLORANTS
Full listing title: PDRN Pink Peptide Serum with Salmon DNA | Ultra Light Hydrating Serum with Hyaluronic Acid | Fast-Absorbing Glow Care for Skin Clarity | Korean Skincare, 3.71 fl. Oz
Frequently asked questions
Is the medicube PDRN Pink Peptide Serum with Salmon good for sensitive skin?
We cannot tell you that. What we can say is that its Amazon listing does not flag strong actives, which is a filter on listing text, not a safety assessment. If your skin is reactive or you have a diagnosed condition, patch test first and ask a pharmacist, GP or dermatologist.
How do you use the medicube PDRN Pink Peptide Serum with Salmon?
Use it after toner, before moisturizer. Follow the directions on the pack, and always finish your morning routine with sunscreen.
Is the medicube PDRN Pink Peptide Serum with Salmon worth it?
For the price, it is an easy recommendation: 4.5 out of 5 from a large number of shoppers, doing a clear job in the routine. Results vary from person to person, so manage expectations.
Check price on Amazon →