Medicube Scalp Serum with Rosemary PDRN

Overview

Medicube markets this on salmon DNA PDRN, and you use it as a targeted treatment step. With a strong 4.4 out of 5 from 449 ratings, it is a well-liked pick. Its Amazon listing does not flag strong actives, which is a filter on listing text rather than a safety assessment.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

At a glance

What buyers actually say

We read a sample of the Amazon reviews for this product and describe the pattern in our own words. It is a sample, not a survey of all 589 ratings, and we do not reproduce customer reviews.

The applicator does much of the selling in our sample. Reviewers like the roller tip for parting hair and reaching the scalp and hairline without mess, describe a light minty tingle, and repeatedly note that it leaves hair non-greasy. Several also dab it on brows. Reports of visible change are early and cautious: fine new hairs along the front hairline, a stylist remarking on thickness, hair that simply feels softer. Volume is the sore point. More than one reviewer says the tube is too small for daily use and empties within weeks, which is what turns an otherwise liked product into a repurchase they hesitate over.

How the ratings break down

Amazon's own star distribution for this product, read on 2026-09-30. We show the one-star share too, because an average alone hides it.

8% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.

We cannot tell you what those reviewers said. Amazon.com now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is salmon DNA PDRN?

PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.

Ingredients, as listed by Medicube

Taken from Medicube's own product page on 2026-08-05. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.

Show the full ingredient list (90 ingredients)

Water (Aqua), Alcohol Denat., C12-13 Alketh-9, Caffeine, Dipropylene Glycol, Hydrolyzed Sponge, Ammonium Acryloyldimethyltaurate/VP Copolymer, Menthol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Fragrance (Parfum), Allantoin, Aminomethyl Propanol, Disodium EDTA, Dipotassium Glycyrrhizate, Ethyl Menthane Carboxamide, Panthenol, Butylene Glycol, 1,2-Hexanediol, Arginine, Gluconolactone, Menthyl Lactate, Ricinus Communis (Castor) Seed Oil, Sodium DNA (100ppb), Glycerin, Glycolic Acid, Saccharide Isomerate, Raphanus Sativus (Radish) Seed Extract, Octyldodecyl Oleate, Octyldodecanol, Hydrolyzed Pea Protein, Hydrolyzed Vegetable Protein, Biotin, Niacinamide, Salicylic Acid, Caprylic/Capric Triglyceride, Hydrogenated Lecithin, Sparassis Crispa Extract, Streptococcus Thermophilus Ferment, Sodium Palmitoyl Sarcosinate, Magnolia Obovata Bark Extract, Hydrolyzed Collagen, Hydrolyzed Corn Protein, Hydrolyzed Extensin, Hydrolyzed Potato Protein, Hydrolyzed Rice Protein, Hydrolyzed Soy Protein, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Prunus Amygdalus Dulcis (Sweet Almond) Extract, Citric Acid, Sodium Citrate, Potassium Sorbate, Sodium Benzoate, Rosmarinus Officinalis (Rosemary) Leaf Extract (0.2ppb), Hydrolyzed Keratin, Caprylyl Glycol, sh-Oligopeptide-1, Alanine, Asparagine, Aspartic Acid, Dimethylsilanol Hyaluronate, Glucose, Glutamic Acid, Glutamine, Glycine, Histidine, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Isoleucine, Leucine, Lysine, Mentha Piperita (Peppermint) Leaf Extract, Methionine, Phenylalanine, Proline, Serine, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-22, sh-Polypeptide-3, sh-Polypeptide-9, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Threonine, Tryptophan, Tyrosine, Valine

What the ingredient order actually tells you

• Alcohol denat sits second of 90. This is a classic stimulating scalp tonic: alcohol carrier, caffeine fourth, a sponge-derived powder sixth, menthol eighth, fragrance tenth. The tingle is the design, not a side effect.
• The salmon DNA earns its billing better than usual at 23rd, and glycolic acid at 25th with salicylic at 34th gives the flake-prone claim something to point at.
• The deep tail is the familiar showcase: collagen 41st, peptides from 56th, hyaluronic entries from 60th onward.

Our read

Judge this as what the top of the list says it is: an alcohol-and-caffeine scalp tonic with a menthol kick, in the tradition of every barbershop hair lotion. The PDRN at 23rd is better placed than in the matching shampoo, but the experience will be defined by alcohol, menthol and fragrance. Fine for a resilient, oily scalp that enjoys the cold-tingle ritual; the wrong tool for an irritated one.

Who should skip this

• Your scalp is sensitive, broken or already irritated. Alcohol denat at second plus menthol at eighth is a punishing combination.
• Fragrance-free hair care is a requirement for you. Fragrance sits tenth of 90 here.
• You expected a leave-on skincare-style serum. This behaves like a tonic, and the sponge powder at sixth adds a physical prickle.

A note on how we read that list. Ingredient lists run in descending order of concentration, but only for ingredients above 1%. Below that, the order is up to the manufacturer, so a low position tells you something is present at a low level, not exactly how much. We do not guess at percentages. FDA labeling guide.

What the listing says

Medicube's own description of this product, as published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not verified the claims in it.

• [TRIPLE-ACTIVE SCALP CARE COMPLEX] Formulated with Rosemary, PDRN, and EGF to help soothe and condition str…
• [TARGETED SCALP CARE WITH SPICULES] Ultra-fine spicules help ingredients apply more evenly, enhancing the s…
• [NON-GREASY, LIGHTWEIGHT QUICK SCALP CARE] Fast-absorbing formula that quickly cools down the scalp and soo…
• [COOLING SCALP CARE WITH GUA SHA APPLICATOR] A concentrated scalp serum featuring a mini gua sha - style appl…
• [HOW TO USE] After shampooing, lightly towel-dry hair to remove excess water.

Full listing title: Scalp Serum with Rosemary PDRN | Non-Greasy, Lightweight Serum for Thicker, Fuller, Denser-Looking Hair | Scalp Treatment for Flake-Prone Scalp, Soothing | Korean Hair Care, 20ml

Frequently asked questions

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