Medicube Rosemary PDRN Clarifying Thickening Shampoo

Overview

The hero ingredient is salmon DNA PDRN, and you use it as a targeted treatment step. With a strong 4.5 out of 5 from 828 ratings, it is a well-liked pick. It is one of the gentler options in the range, so it suits most skin types including sensitive skin.

The summary above follows how Medicube markets this product. We also read the published ingredient list line by line, and it tells a different story: what the ingredient order actually says.

At a glance

How the ratings break down

Amazon's own star distribution for this product, read on 2026-10-28. We show the one-star share too, because an average alone hides it.

9% of these ratings are one or two stars. That is about typical for the Medicube range, where the median is 6%.

We cannot tell you what those reviewers said. Amazon.com now requires an account to open the full review list, so the critical reviews are not readable from a public page. We would rather say that than guess.

What is salmon DNA PDRN?

PDRN (polydeoxyribonucleotide) is a soothing, skin-conditioning ingredient derived from salmon DNA, used to support the barrier and give a plumper, glowier look.

Ingredients, as listed by Medicube

Taken from Medicube's own product page on 2026-08-05. We have not verified it against a physical pack, and formulations change by market and batch. If an ingredient matters to you, check the pack itself.

Show the full ingredient list (107 ingredients)

Water (Aqua), Sodium Cocoyl Isethionate, Disodium Laureth Sulfosuccinate, Glycerin, Cocamidopropyl Hydroxysultaine, Lauryl Betaine, Glyceryl Stearate, Sodium Lauroyl Methylaminopropionate, Menthol, Trihydroxystearin, Sodium Chloride, Fragrance (Parfum), Sodium Benzoate, Cetyl Alcohol, Dicaprylyl Ether, Polyquaternium-10, Panthenol, Salicylic Acid, Citric Acid, Caprylyl Glycol, Niacinamide, Tetrasodium EDTA, Zea Mays (Corn) Starch, Mannitol, Microcrystalline Cellulose, Linalool, Carthamus Tinctorius (Safflower) Flower Extract, Dextrin, Gardenia Florida Fruit Extract, Chromium Oxide Greens, Ultramarines, Chromium Hydroxide Green, Tocopheryl Acetate, Hydrogenated Lecithin, Tocopherol, Butylene Glycol, Sodium Citrate, Caffeine, Arginine, Dipropylene Glycol, Gluconolactone, Menthyl Lactate, PPG-14 Butyl Ether, Ricinus Communis (Castor) Seed Oil, Glycolic Acid, Saccharide Isomerate, Sodium C14-16 Olefin Sulfonate, 1,2-Hexanediol, Hydrolyzed Pea Protein, Hydrolyzed Vegetable Protein, Caprylic/Capric Triglyceride, Raphanus Sativus (Radish) Seed Extract, Sodium Palmitoyl Sarcosinate, Octyldodecyl Oleate, Octyldodecanol, Sparassis Crispa Extract, Streptococcus Thermophilus Ferment, Hydrolyzed Collagen, Hydrolyzed Corn Protein, Hydrolyzed Extensin, Hydrolyzed Potato Protein, Hydrolyzed Rice Protein, Hydrolyzed Soy Protein, Melaleuca Alternifolia (Tea Tree) Leaf Extract, Prunus Amygdalus Dulcis (Sweet Almond) Extract, Potassium Sorbate, Sodium DNA (2.5 ppb), Magnolia Obovata Bark Extract, Hydrolyzed Keratin, Disodium EDTA, Rosmarinus Officinalis (Rosemary) Leaf Extract (0.25 ppb), Biotin, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-11, sh-Polypeptide-22, sh-Polypeptide-3, sh-Polypeptide-9, Alanine, Asparagine, Aspartic Acid, Dimethylsilanol Hyaluronate, Glucose, Glutamic Acid, Glutamine, Glycine, Histidine, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Isoleucine, Leucine, Lysine, Mentha Piperita (Peppermint) Leaf Extract, Methionine, Phenylalanine, Proline, Serine, Sodium Acetylated Hyaluronate, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Threonine, Tryptophan, Tyrosine, Valine

What the ingredient order actually tells you

• At 107 entries this is the longest list in the range, and the top of it tells you what kind of product this is: menthol ninth, fragrance 12th, panthenol 17th, salicylic acid 18th. A tingly, scented clarifying shampoo with the salicylic acid placed where it can actually matter.
• The wash base leans mild: sodium cocoyl isethionate second and a sulfosuccinate third, rather than the harsher sulfates.
• The skincare celebrity section is a long walk to the back: caffeine 38th, collagen 58th, salmon DNA at 67th of 107, peptides from 73rd, hyaluronic entries from 83rd.
• Rosemary is present under its Latin name, Rosmarinus Officinalis, at 71st of 107.

Our read

As a clarifying shampoo the working half of the list is competently built: milder-leaning surfactants, menthol for the fresh scalp feel, salicylic acid at 18th. The PDRN and peptide branding sits far down the list at 67th and beyond, and in a product you rinse straight out it was never going to be more than branding. Buy the shampoo, not the biotech.

Who should skip this

• Fragrance or menthol on the scalp sets you off. They sit 12th and ninth, right up front.
• You are paying a premium for salmon DNA. At 67th of 107, in a rinse-off, it is a sticker.
• You wanted a rosemary-oil scalp routine. Rosemary leaf extract is on the list, but at 71st of 107 in a product you rinse off.

A note on how we read that list. Ingredient lists run in descending order of concentration, but only for ingredients above 1%. Below that, the order is up to the manufacturer, so a low position tells you something is present at a low level, not exactly how much. We do not guess at percentages. FDA labeling guide.

What the listing says

Medicube's own description of this product, as published on its Amazon.com listing. It is marketing copy, not our assessment, and we have not verified the claims in it.

• [STRENGTHEN & VOLUMIZE THIN-LOOKING HAIR] Designed for fine, fine, thin-looking hair - helps strengthen strands from root to tip while boosting the look of volume, bounce, and healthy shine.
• [STRONGER SCALP, STRONGER STRANDS] Powered by Rosemary PDRN to help support a healthier scalp environment, reinforce weak strands, and reduce breakage for fuller-looking, more resilient hair.
• [FOR ALL HAIR TYPES & TEXTURES] This lightweight formula nourishes without heaviness, helping improve softness while enhancing natural-looking volume and movement.
• [COOLING SCALP CARE & BUILDUP CONTROL] Delivers a refreshing cooling sensation with a clean mint scent while helping remove excess oil and buildup that can weigh hair down and affect volume.
• [GENTLE YET EFFECTIVE FOR DAILY USE] Gentle yet effective for daily use - helps maintain a balanced, comfortable scalp while continuously supporting stronger, healthier-looking hair.

Full listing title: medicube Rosemary PDRN Clarifying Thickening Shampoo, 13.52 fl.oz

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